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Details for Patent: 5,080,887

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Details for Patent: 5,080,887

Title: Antibacterial antiplaque, anticalculus oral composition
Abstract:An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncatationic antibacterial agent such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (Triclosan).
Inventor(s): Gaffar; Abdul (Princeton, NJ), Nabi; Nuran (North Brunswick, NJ), Jannone; Brian S. (Basking Ridge, NJ)
Assignee: Colgate-Palmolive Company (Piscataway, NJ)
Filing Date:Aug 08, 1991
Application Number:07/741,910
Claims:1. An oral composition comprising, in an orally acceptable vehicle, an effective anticalculus amount of at least one water soluble linear molecularly dehydrated polyphosphate salt as essential anticalculus agent, an effective antiplaque amount of a substantially water insoluble noncationic antibacterial compound as essential antiplaque agent, and:

A. an amount of a fluoride ion-providing source sufficient to supply about 25 ppm. to about 2,000 ppm. of fluoride ions; or

B. about 0.05% to about 3% of a water soluble synthetic anionic polymeric polycarboxylate; or

C. mixtures of A and B.

2. An oral composition according to claim 1 containing A wherein said fluoride ion-providing source comprises sodium fluoride, sodium monofluorophosphate, or a mixture thereof.

3. An oral composition according to claim 1 containing B or C wherein said fluoride ion-providing source comprises sodium fluoride, sodium monofluorophosphate or a mixture thereof and said polycarboxylate comprises a salt of a copolymer of maleic acid or anhydride with methylvinylether.

4. An oral composition according to claim 3 wherein said antibacterial compound comprises a halogenated diphenyl ether.

5. An oral composition according to claim 4 wherein said antibacterial compound comprises Triclosan.

6. An oral composition according to any one of claims 1 to 5 in the form of a toothpaste, cream or gel containing a dentally acceptable polishing agent.

7. An oral composition according to any one of claims 1 to 5 in the form of a mouthwash containing a water/humectant vehicle.

8. An oral composition comprising, in an orally acceptable vehicle, a dentally acceptable silica polishing agent, an effective anticalculus amount of at least one water soluble linear molecularly dehydrated polyphosphate salt as essential anticalculus agent, an effective antiplaque amount of a substantially water insoluble noncationic antibacterial compound as essential antiplaque agent, and:

A. an amount of a fluoride ion-providing source sufficient to supply about 25 ppm. to about 2,000 ppm. of fluoride ions; or

B. about 0.05% to about 3% of a water soluble synthetic anionic polymeric polycarboxylate; or

C. mixtures of A and B.

9. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in any one of claims 1 to 5 and 8.
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