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Serving leading biopharmaceutical companies globally:

Argus Health
Federal Trade Commission
Boehringer Ingelheim
Harvard Business School
Queensland Health

Generated: December 17, 2017

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Title: 6-substituted purine carbocyclic nucleosides
Abstract:The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invention.
Inventor(s): Daluge; Susan M. (Chapel Hill, NC)
Assignee: Burroughs Wellcome Co. (Research Triangle Park, NC)
Filing Date:Dec 22, 1989
Application Number:07/455,538
Claims:1. A compound (.+-.)-cis-4-(2-amino-6-(allylthio)-9H-purin-9-yl)-2-cyclopentene-1-methan ol.

2. A compound (.+-.)-cis-4-(2-amino-6-cyclopentyloxy-9H-purin-9-yl)-2-cyclopentene-1-met hanol.

3. A compound (.+-.)-cis-4-(2-amino-6-(Allylamino)-9H-purin-9-yl)-2-cyclopentene-1-metha nol.

4. A compound (.+-.)-cis-4-(2-amino-6-(cyclopentylthio)-9H-purin-9-yl)-2-cyclopentene-1- methanol.

5. A compound (.+-.)-cis-4-(2-amino-6-(cyclopbutylthio)-9H-purin-9-yl)-2-cyclopentene-1- methanol.
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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Daiichi Sankyo
Fish and Richardson
US Department of Justice

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