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Details for Patent: 5,043,154

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Details for Patent: 5,043,154

Title: Antibacterial, antiplaque, anticalculus oral composition
Abstract:An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (Triclosan).
Inventor(s): Gaffar; Abdul (Princeton, NJ), Nabi; Nuran (North Brunswick, NJ), Jannone; Brian S. (Basking Ridge, NJ)
Assignee: Colgate-Palmolive Co. (New York, NY)
Filing Date:May 01, 1989
Application Number:07/346,258
Claims:1. An oral composition comprising in an orally acceptable vehicle, an effective anticalculus amount of at least one water soluble linear molecularly dehydrated polyphosphate salt as essential anticalculus agent and an effective antiplaque amount of a substantially water insoluble noncationic antibacterial compound as essential antiplaque agent.

2. An oral composition according to claim 1 wherein said polyphosphate salt comprises sodium tripolyphosphate.

3. An oral composition according to claim 1 wherein the substantially water insoluble noncationic antibacterial compound is a phenolic compound.

4. An oral composition according to claim 3 wherein said antibacterial phenolic compound comprises hexyl resorcinol.

5. An oral composition according to claim 4 wherein said polyphosphate salt comprises sodium tripolyphosphate.

6. An oral composition according to claim 5 further containing as essential inhibitor of salivary enzymatic hydrolysis of the sodium tripolyphosphate an amount of a fluoride ion-providing source sufficient to supply about 25 ppm. to about 2,000 ppm of fluoride ions.

7. An oral composition according to claim 6 further containing as essential inhibitor of salivary enzymatic hydrolysis of the sodium tripolyphosphate about 0.05% to about 3% of a water soluble synthetic anionic polymeric polycarboxylate salt having a molecular weight of about 1,000 to about 1,000,000.

8. An oral composition according to claim 7 wherein said water soluble polycarboxylate salt is an alkali metal or ammonium salt of a copolymer of vinyl methyl ether and maleic acid or anhydride having a molecular weight of about 30,000 to about 500,000.

9. An oral composition according to claim 8 in the form of a toothpaste containing a dentally acceptable water insoluble polishing agent.

10. An oral toothpaste composition according to claim 9 containing a silica polishing agent.

11. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 1.

12. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 2.

13. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 3.

14. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 4.

15. A method inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 5.

16. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 6.

17. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 7.

18. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 8.

19. A method of inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 9.

20. A method inhibiting dental plaque and calculus comprising applying to teeth plaque and calculus inhibiting amounts of an oral composition as defined in claim 10.
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