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Details for Patent: 4,987,152

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Details for Patent: 4,987,152

Title: Use of sulfamoyl-substituted phenethylamine derivatives in treatment of lower urinary tract dysfunction
Abstract:Novel sulfamoyl-substituted phenethylamine derivatives which exhibit .alpha.-adrenergic blocking action and are useful as an antihypertensive agent and an agent for the treatment of congestive heart failure.
Inventor(s): Imai; Kazuo (Saitama, JP), Niigata; Kunihiro (Saitama, JP), Fujikura; Takashi (Saitama, JP), Hashimoto; Shinichi (Chiba, JP)
Assignee: Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP)
Filing Date:Nov 13, 1989
Application Number:07/436,125
Claims:1. A method of treating lower urinary tract dysfunction which comprises administering the compound represented by the formula ##STR87## wherein R.sub.1 represents an amino group or a mono-or di-lower alkylamino group; R.sub.2 represents a hydroxyl group, a lower alkyl group, or a lower alkoxy group, R.sub.3 represents hydrogen atom, halogen atom, a lower alkyl group, a lower alkoxy group, a phenylthio group, or a phenylsulfinyl group; R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 each represents hydrogen atom or a lower alkyl group; R.sub.10 represents hydrogen atom, a lower alkyl group, or a lower alkoxy group, and Y represents an oxygen atom or a methylene group; said Y being an oxygen atom when R.sub.2 is a hydroxyl group; or the salts thereof.
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