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Serving leading biopharmaceutical companies globally:

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Federal Trade Commission
Farmers Insurance
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Moodys
UBS
Johnson and Johnson
Cerilliant
Argus Health

Generated: October 22, 2017

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Title: Optically active pyridobenzoxazine derivatives and intermediates thereof
Abstract:An optically action pyridobenzoxazine derivative, a process for preparing the same and a novel intermediate useful for preparing the optically active pyridobenzoxazine derivative are disclosed. The optically active pyridobenzoxazine derivative possesses increased antimicrobial activity and reduced toxicity. The intermediate is useful for preparing such optically active pyridobenzoxazine derivatives such as Ofloxacin and anolog compounds.
Inventor(s): Hayakawa; Isao (Tokyo, JP), Atarashi; Shohgo (Tokyo, JP), Imamura; Masazumi (Tokyo, JP), Yokohama; Shuichi (Tokyo, JP), Higashihashi; Nobuyuki (Tokyo, JP), Sakano; Katsuichi (Tokyo, JP), Ohshima; Masayuki (Tokyo, JP)
Assignee: Daiichi Seiyaku Co., Ltd. (Tokyo, JP)
Filing Date:Mar 23, 1989
Application Number:07/327,653
Claims:1. An isolated 4-substituted benzoxazine derivative represented by the formula (X) ##STR9## wherein X.sub.1 and X.sub.2, which may be the same or different, each represents a halogen atom, R.sub.1 represents an alkyl group having 1 to 4 carbon atoms, and Q represents a group ##STR10## wherein R.sub.2 represents a substituted sulfonyl group, an alkoxycarbonyl group or an aralkyloxycarbonyl group, and n represents an integer of 1 to 3.
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Serving leading biopharmaceutical companies globally:

US Department of Justice
Daiichi Sankyo
Express Scripts
Accenture
Healthtrust
UBS
Argus Health
Cantor Fitzgerald
Merck
Moodys

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