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Details for Patent: 4,923,805

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Details for Patent: 4,923,805

Title: FSH
Abstract:Biologically active heterodimeric human FSH composed of an alpha subunit and a beta subunit, each subunit being synthesized by a cell having an expression vector containing heterologous DNA encoding the subunit.
Inventor(s): Reddy; Vemuri B. (Framingham, MA), Hsiung; Nancy (Wellesley, MA), Beck; Anton K. (Chestnut Hill, MA), Berstine; Edward G. (Boston, MA)
Assignee: Integrated Genetics, Inc. (Framingham, MA)
Filing Date:Jan 30, 1985
Application Number:06/696,647
Claims:1. A method for producing biologically active, heterodimeric human FSH comprising culturing mammalian cells capable of glycosylating proteins, said cells comprising an expression vector encoding the alpha and beta subunits of said FSH.

2. A vector comprising a DNA sequence encoding the beta subunit of human FSH.
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