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Details for Patent: 4,873,335

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Details for Patent: 4,873,335

Title: 3-phenethyl-2-benzene-amides or aza-derivatives thereof
Abstract:Compounds of the formula: ##STR1## are produced, with the variables as indicated within.
Inventor(s): Schumacher; Doris P. (Florham Park, NJ), Murphy; Bruce L. (Elizabeth, NJ), Clark; Jon E. (Highland Park, NJ)
Assignee: Schering Corporation (Kenilworth, NJ)
Filing Date:Dec 02, 1987
Application Number:07/127,743
Claims:1. A compound of the formula IV ##STR24## wherein: a, b, c and d represent CH or one of a, b, c and d represents N and the others represent CH;

R.sup.1, R.sup.2, R.sup.3 and R.sup.4 may be the same or different and each independently represents hydrogen, alkyl having from 1 to 6 carbon atoms, halogen, nitro, alkoxy having from 1 to 6 carbon atoms or trifluoromethyl; and

R.sup.6 represents a tertiary butyl group.

2. A compound according to claim 1, wherein R.sup.2 and R.sup.3 may be the same or different and each is selected from hydrogen or halo; R.sup.1 and R.sup.4 are hydrogen; d is N; and a, b, and c are CH.

3. A compound according to claim 1, wherein R.sup.2 is H, chloro or fluoro; R.sup.1, R.sup.3 and R.sup.4 are hydrogen; d is N; and a, b, and c are CH.

4. A compound according to claim 3, wherein R.sup.2 is chloro.

5. A compound according to claim 3, wherein R.sup.2 is H.

6. A compound of the formula XV ##STR25## or an acid addition salt thereof.

7. A compound according to claim 6, which is the hydrochloride salt thereof.
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