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Details for Patent: 4,857,511

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Details for Patent: 4,857,511

Title: Treatment of human viral infections
Abstract:Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
Inventor(s): Rideout; Janet L. (Raleigh, NC), Barry; David W. (Chapel Hill, NC), Lehrman; Sandra N. (Durham, NC), St. Clair; Martha H. (Durham, NC), Furman; Phillip A. (Durham, NC)
Assignee: Burroughs Wellcome Co. (Research Triangle Park, NC)
Filing Date:Feb 08, 1988
Application Number:07/152,977
Claims:1. A method of treating a human having AIDS and who is also being administered acyclovir, which comprises administering to said human an effective AIDS treatment amount of the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable salt thereof.

2. A method of claim 1, in which the compound 3'-azido-3'-deoxythymidine is administered orally or by injection.

3. A method of claim 1, in which the compound or salt thereof is administered orally or by injection.
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