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Details for Patent: 4,832,952

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Details for Patent: 4,832,952

Title: Pharmaceutical composition containing a liquid lubricant
Abstract:Pharmaceutical compositions produced with liquid, hydrophilic lubricants possessing markedly improved dissolution rates.
Inventor(s): Hersh; Marvin (Strafford, PA), Lentine; Charles W. (Brookhaven, PA)
Assignee: American Home Products Corporation (New York, NY)
Filing Date:Jul 21, 1986
Application Number:06/888,533
Claims:1. A solid pharmaceutical composition free of solid hydrophobic lubricant comprising a dry, powdery, dust-producing formulation of a therapeutic agent, in intimate admixture with a non-solubilizing amount of a pharmaceutically acceptable, liquid, hydrophilic, dust-reducing, lubricant, said lubricant being a polyethylene glycol of molecular weight from about 200 to about 900, present in said admixture in from about 0.2 to about 5 weight percent of composition.

2. A solid pharmaceutical composition of claim 1 in which said polyethylene glycol has a molecular weight of about 380 to about 420.

3. A solid pharmaceutical composition of claim 1 in which said admixture contains a pharmaceutically acceptable surface active agent.
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