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Details for Patent: 4,818,768

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Details for Patent: 4,818,768

Title: Process for the treatment of hyperpigmentary dermatoses including malignant melanomas
Abstract:There is disclosed a composition for the treatment of acne, hyperpigmentary dermatoses or skin hyperpigmentation which contains dicarboxylic acids containing 7 to 13 carbon atoms or certain derivatives thereof that contain reducing functional group or a salt thereof. There are also disclosed methods for preparing mercapto derivatives of these discarboxylic acids.
Inventor(s): Nazzaro-Porro; Marcella (Rome, IT)
Assignee: Schering AG (Berlin, DE)
Filing Date:Jan 29, 1982
Application Number:06/343,745
Claims:1. A method for the treatment of individuals exhibiting a malignant melanoma or a circumscribed precancerous melanosis of Dubreuihl condition which comprises administering to said individual a therapeutically effective amount of at least one dicarboxylic acid selected from the group consisting of azelaic acid and dodecandioic acid, in a phramaceutically acceptable carrier until said condition is reduced or its further development is arrested.

2. A method as defined in claim 1, wherein said acid is azelaic acid.

3. A method as defined in claim 2 wherein said individual exhibits a malignant melanoma condition.

4. A method as defined in claim 2 wherein said individual exhibits a circumscribed pre-cancerous melanosis of Dubreuilh condition.

5. A method as defined in claim 1 wherein said acid is dodecandioic acid.

6. A method as defined in claim 5 wherein said individual exhibits a malignant melanoma condition.

7. A method as defined in claim 5 wherein said individual exhibits a circumscribed pre-cancerous melanosis of Dubreuilh condition.
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