DrugPatentWatch Database Preview
Details for Patent: 4,818,768
| Title: | Process for the treatment of hyperpigmentary dermatoses including malignant melanomas |
| Abstract: | There is disclosed a composition for the treatment of acne, hyperpigmentary dermatoses or skin hyperpigmentation which contains dicarboxylic acids containing 7 to 13 carbon atoms or certain derivatives thereof that contain reducing functional group or a salt thereof. There are also disclosed methods for preparing mercapto derivatives of these discarboxylic acids. |
| Inventor(s): | Nazzaro-Porro; Marcella (Rome, IT) |
| Assignee: | Schering AG (Berlin, DE) |
| Filing Date: | Jan 29, 1982 |
| Application Number: | 06/343,745 |
| Claims: | 1. A method for the treatment of individuals exhibiting a malignant melanoma or a circumscribed precancerous melanosis of Dubreuihl condition which comprises administering to said individual a therapeutically effective amount of at least one dicarboxylic acid selected from the group consisting of azelaic acid and dodecandioic acid, in a phramaceutically acceptable carrier until said condition is reduced or its further development is arrested. 2. A method as defined in claim 1, wherein said acid is azelaic acid. 3. A method as defined in claim 2 wherein said individual exhibits a malignant melanoma condition. 4. A method as defined in claim 2 wherein said individual exhibits a circumscribed pre-cancerous melanosis of Dubreuilh condition. 5. A method as defined in claim 1 wherein said acid is dodecandioic acid. 6. A method as defined in claim 5 wherein said individual exhibits a malignant melanoma condition. 7. A method as defined in claim 5 wherein said individual exhibits a circumscribed pre-cancerous melanosis of Dubreuilh condition. |
