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Details for Patent: 4,808,592

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Details for Patent: 4,808,592

Title: Method of treating diseases by administering morpholinoethylester of mycophenolic acid and derivatives thereof
Abstract:The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, anti-inflammatory agents, anti-tumor agents, anti-viral agents, and anti-psoriatic agents. ##STR1##
Inventor(s): Nelson; Peter H. (Los Altos, CA), Gu; Chee-Liang L. (Sunnyvale, CA), Allison; Anthony C. (Belmont, CA), Eugui; Elsie M. (Belmont, CA), Lee; William A. (Menlo Park, CA)
Assignee: Syntex (U.S.A.) Inc. (Palo Alto, CA)
Filing Date:Sep 04, 1987
Application Number:07/093,459
Claims:1. A method of treating inflammatory, and psoriatic diseases in mammals, which comprises administering to a mammal suffering therewith a therapeutically effective amount of a compound represented by the formula: ##STR7## wherein: Z is hydrogen or --C(O)R, where R is lower alkyl or aryl; or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 comprising a method of treating rheumatoid arthritis in mammals.
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