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Mallinckrodt
Chubb
Fish and Richardson
Cantor Fitzgerald
US Department of Justice
Covington
Cipla
Merck
Farmers Insurance

Generated: June 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,761,500

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Title: Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them
Abstract:A novel process is provided for the preparation of optical isomers of certain sulfamoyl-substituted phenethylamine derivatives which exhibit .alpha.-adrenergic blocking agents which can be used for various treatments such as for the treatment of congestive heart failure.
Inventor(s): Niigata; Kunihiro (Saitama, JP), Fujikura; Takashi (Saitama, JP)
Assignee: Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP)
Filing Date:Feb 10, 1986
Application Number:06/828,052
Claims:1. A process of producing (R)(-)-5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino-2-methylethyl]-2-methoxybenze nesulfonamide, which comprises reacting (R)(-)-5-[(2-amino-2-methyl)ethyl]-2-methoxybenzenesulfonamide with 2-(o-ethoxyphenoxy)ethyl bromide.

2. A process of producing (S)(+)-5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino]-2-methylethyl]-2-methoxybenz enesulfonamide, which comprises reacting (S)(+)-5-[(2-amino-2-methyl)ethyl]-2-methoxybenzenesulfonamide with 2-(o-ethoxyphenoxy)ethyl bromide.

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Johnson and Johnson
Dow
Deloitte
Citi
Cantor Fitzgerald
Baxter
McKinsey
Julphar

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