|Title:||Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them|
|Abstract:||A novel process is provided for the preparation of optical isomers of certain sulfamoyl-substituted phenethylamine derivatives which exhibit .alpha.-adrenergic blocking agents which can be used for various treatments such as for the treatment of congestive heart failure.|
|Inventor(s):||Niigata; Kunihiro (Saitama, JP), Fujikura; Takashi (Saitama, JP)|
|Assignee:||Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP)|
|Filing Date:||Feb 10, 1986|
|Claims:||1. A process of producing (R)(-)-5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino-2-methylethyl]-2-methoxybenze nesulfonamide, which comprises reacting (R)(-)-5-[(2-amino-2-methyl)ethyl]-2-methoxybenzenesulfonamide with 2-(o-ethoxyphenoxy)ethyl bromide. |
2. A process of producing (S)(+)-5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino]-2-methylethyl]-2-methoxybenz enesulfonamide, which comprises reacting (S)(+)-5-[(2-amino-2-methyl)ethyl]-2-methoxybenzenesulfonamide with 2-(o-ethoxyphenoxy)ethyl bromide.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.