Manage your formulary budget
Drug patents …
… from Kazakhstan to Kalamazoo
Find generic entry opportunities
Deep knowledge on
small-molecule drugs and
the 110,000 global patents
Proactively manage your pharmacy inventory
Anticipate generic drug launch
Flat-rate pricing for predictable budgeting
Short-term plans for project- or client-based billing
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Medical bandage for administering vasodilator drug|
|Abstract:||A medical bandage is disclosed comprising a reservoir containing a gelled fluid, rheological agent and a drug. A method of using the bandage for producing a beneficial effect is disclosed also.|
|Inventor(s):||Gale; Robert M. (Mountain View, CA)|
|Assignee:||ALZA Corporation (Palo Alto, CA)|
|Filing Date:||Jun 09, 1986|
|Claims:||1. A medical bandage for the administration of a drug to the skin, the medical bandage consisting essentially of: |
(a) a backing member that is substantially impermeable to the passage of drug, the backing member consisting essentially of polyethylene, aluminized polyethylene-terephthalate, and ethylene-vinyl actate compolymer;
(b) a reservoir in contact with the backing member, the reservoir consisting essentially of a silicone, from about 0.1 to about 25% of silicon dioxide, and from 0.1 to about 70% of a dosage amount of a vasodilator drug having a member selected from the group consisting of ONO and ONO.sub.2 ; and,
(c) a membrane positioned opposite the backing member and in contact with the reservoir for releasing drug from the medical bandage, said membrane consisting essentially of ethylene-vinyl acetate copolymer and in contact with the backing member to form the medical bandage.
2. The medical bandage for the administration of the drug to the skin according to claim 1, wherein the membrane and the backing member contact along their perimeters in a fluid tight arrangement to provide the medical bandage.
3. The medical bandage for the administration of the drug to the skin according to claim 1, wherein an adhesive is in contact with the membrane.
4. The medical bandage for the administration of the drug to the skin according to claim 1, wherein the vasodilator drug is nitroglycerin.
5. The medical bandage for the administration of the drug to the skin according to claim 1, wherein the membrane releases the drug at the rate of about 10 to 2000 .mu.g/hr from the medical bandage.
6. The medical bandage for the administration of the drug to the skin according to claim 1, wherein the medical bandage releases drug to a skin that exhibits a flux of about 70 to 90 .mu.g/cm.sup.2 for the drug.
7. The medical bandage for the administration of the drug to the skin according to claim 1, wherein the backing member consists essentially of a lamina of polyethlyene, a lamina of aluminum vapor deposited on polythylene-terephthalate, and a lamina of ethylene-vinyl acetate copolymer.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.