Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

US Department of Justice
Johnson and Johnson
Chinese Patent Office

Generated: April 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,596,795

« Back to Dashboard

Title: Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
Abstract:The administration of sex hormones, particularly testosteorne, progesterone and estradiol in the form of their complexes or inclusions with specific derivatives of cyclodextrins by the sublingual or buccal route results in effective transfer of these hormones into the systemic circulation, followed by only gradual elimination. To be effective in the above mode of administration, the derivatives of cyclodextrins must carry one or several substituents, each containing one or several hydroxy groups. Specially preferred are the following complexes: hydroxypropylbeta-cyclodextrin and poly-beta-cyclodextrin.
Inventor(s): Pitha; Josef (Baltimore, MD)
Assignee: The United States of America as represented by the Secretary, Dept. of (Washington, DC)
Filing Date:Apr 25, 1984
Application Number:06/603,839
Claims:1. A method of treating a human by sex hormone addition which comprises injecting by the buccal route a regimen of 0.1-25 mg per diem of a compound consisting of testosterone, progesterone, and estradiol as an inclusion complex with poly-.beta.-cyclodextrin or hydroxypropyl-.beta.-cyclodextrin.

2. The method of claim 1 wherein poly-.beta.-cyclodextrin is utilized.

3. The method of claim 1 wherein hydroxypropyl-.beta.-cyclodextrin is utilized.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Chinese Patent Office
Farmers Insurance

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.