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Details for Patent: 4,540,583

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Details for Patent: 4,540,583

Title: Method of treating tumors in warm-blooded animals
Abstract:This disclosure describes novel compositions of matter useful as growth inhibitors of transplanted tumors in mammals and the method of inducing the regression and/or palliation of leukemia and solid tumors in mammals therewith, the active ingredients of said compositions of matter being certain symmetrical 1,4-bis(substituted-amino)anthraquinones and the non-toxic acid-addition salts thereof.
Inventor(s): Murdock; Keith C. (Pearl River, NY), Durr; Frederick E. (Ridgewood, NJ)
Assignee: American Cyanamid Company (Stamford, CT)
Filing Date:Dec 08, 1980
Application Number:06/214,147
Claims:1. The method of inducing regression of leukemia and/or inhibiting growth of tumors in a mammal comprising administering to said mammal an effective antineoplastic amount of a compound selected from the group consisting of those of the formula: ##STR4## wherein Q is amino, methylamino, ethylamino, dimethylamino, or diethylamino, the leuco bases and tautomers thereof, and the pharmacologically acceptable acid-addition salts thereof.
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