Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Daiichi Sankyo
McKinsey
Federal Trade Commission
Merck
Teva
Deloitte
Baxter
Moodys

Generated: June 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,526,989

« Back to Dashboard

Title: 1,4-Bis (substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
Abstract:This disclosure describes symmetrical 1,4-bis (substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
Inventor(s): Murdock; Keith C. (Pearl River, NY), Durr; Frederick E. (Ridgewood, NJ)
Assignee: American Cyanamid Company (Stamford, CT)
Filing Date:Oct 23, 1979
Application Number:06/087,354
Claims:1. A compound selected from the group consisting of 1,4-bis[(2-aminoethyl)amino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof, and the pharmacologically acceptable acid-addition salts thereof.

2. The aromatic free base according to claim 1.

3. The leuco free base according to claim 1.

4. The acid-addition salt of the aromatic base according to claim 1 wherein the acid is sulfuric acid.

5. The acid-addition salt of the leuco base according to claim 1 wherein the acid is phosphoric acid.

6. The acid-addition salt of the aromatic base according to claim 1 wherein the acid is hydrochloric acid.

7. The acid-addition salt of the leuco base according to claim 1 wherein the acid is hydrobromic acid.

8. The acid-addition salt of the aromatic base according to claim 1 wherein the acid is sulfamic acid.

9. The acid-addition salt of the leuco base according to claim 1 wherein the acid is citric acid.

10. The acid-addition salt of the aromatic base according to claim 1 wherein the acid is lactic acid.

11. The acid-addition salt of the leuco base according to claim 1 wherein the acid is malic acid.

12. The acid-addition salt of the aromatic base according to claim 1 wherein the acid is succinic acid.

13. The acid-addition salt of the leuco base according to claim 1 wherein the acid is tartaric acid.

14. The acid-addition salt of the aromatic base according to claim 1 wherein the acid is acetic acid.

15. The acid-addition salt of the leuco base according to claim 1 wherein the acid is benzoic acid.

16. The acid-addition salt of the aromatic base according to claim 1 wherein the acid is gluconic acid.

17. The acid-addition salt of the leuco base according to claim 1 wherein the acid is ascorbic acid.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Moodys
McKinsey
Chubb
Julphar
Deloitte
Colorcon
US Army
Medtronic

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.