Serving leading biopharmaceutical companies globally:
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
Serving leading biopharmaceutical companies globally:
Generated: October 20, 2017
| Title: | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)-methyl-1H-imida zoles and 1H-1,2,4-triazoles |
| Abstract: | Novel heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazol es and 1H-1,2,4-triazoles, useful as intermediates and as antifungal and antibacterial agents. |
| Inventor(s): | Heeres; Jan (Vosselaar, BE), Backx; Leo J. J. (Arendonk, BE) |
| Assignee: | Janssen Pharmaceutica N.V. (Beerse, BE) |
| Filing Date: | Sep 28, 1982 |
| Application Number: | 06/425,370 |
| Claims: | 1. A chemical compound having the formula ##STR68## and the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof, wherein: Q is a member selected from the group consisting of CH and N; Ar is a member selected from the group consisting of phenyl, thienyl, halothienyl and substituted phenyl, said substituted phenyl having from 1 to 3 substituents each independently selected from the group consisting of halo, lower alkyl, lower alkyloxy and trifluoromethyl. 2. A chemical compound selected from the group consisting of cis-4-[4-[4-[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl-methyl)-1,3-dioxol an-4-ylmethoxy]phenyl]-1-piperazinyl]benzenamine and the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof. 3. A chemical compound selected from the group consisting of cis-4-[4-[4-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl-methyl)-1,3-d ioxolan-4-ylmethoxy]phenyl]-1-piperazinyl]benzenamine and the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof. |
Serving leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Follow DrugPatentWatch:
Join the 22,963 others who get our Drug Patent Expiration Alerts:
