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QuintilesIMS

Generated: June 18, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,430,501

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Title: 1,4-Bis(substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
Abstract:This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
Inventor(s): Murdock; Keith C. (Pearl River, NY), Durr; Frederick E. (Ridgewood, NJ)
Assignee: American Cyanamid Company (Stamford, CT)
Filing Date:Nov 02, 1981
Application Number:06/244,452
Claims:1. A compound selected from the group consisting of 1,4-bis[2-(1,3-oxazolidin-1-yl)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof, and the pharmaceutically acid-addition salts thereof.

2. A compound selected from the group consisting of 1,4-bis[2-(tetrahydro-1,3-oxazin-1-yl)ethylamino]-5,8-dihydroxyanthraquino ne, the leuco base and tautomer thereof, and the pharmaceutically acceptable acid-addition salts thereof.

3. A compound selected from the group consisting of 1,4-bis[2-(1,3-oxazolidin-2-one-1-yl)ethylamino]-5,8-dihydroxyanthraquinon e, the leuco base and tautomer thereof, and the pharmaceutically acceptable acid-addition salts thereof.

4. A compound selected from the group consisting of 1,4-bis[2-(tetrahydro-1,3-oxazin-2-one-1-yl)ethylamino]-5,8-dihydroxyanthr aquinone, the leuco base and tautomer thereof, and the pharmaceutically acceptable acid-addition salts thereof.

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Chinese Patent Office
Farmers Insurance
Merck
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Julphar
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