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Serving hundreds of leading biopharmaceutical companies globally:

US Army
Boehringer Ingelheim
Daiichi Sankyo

Generated: May 26, 2018

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Details for Patent: 4,337,204

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Title: PGI.sub.2 Lower alkyl esters
Abstract:The present invention relates to PGI.sub.2 lower alkyl esters, having pharmacological activity. Particularly, the compounds described herein are useful as platelet aggregation inhibitors.
Inventor(s): Johnson; Roy A. (Kalamazoo, MI), Lincoln; Frank H. (Portage, MI), Pike; John E. (Kalamazoo, MI)
Assignee: The Upjohn Company (Kalamazoo, MI)
Filing Date:Mar 27, 1981
Application Number:06/248,637
Claims:1. A compound of the formula ##STR2## or a mixture comprising that compound and the enantiomer thereof, wherein R.sub.3 is alkyl of one to 4 carbon atoms, inclusive; including the lower alkanoates thereof.

2. (5Z)-9-Deoxy-6,9.alpha.-epoxy-.DELTA..sup.5 -PGF.sub.1, methyl ester, a compound according to claim 1.

3. (5Z)-9-Deoxy-6,9.alpha.-epoxy-.DELTA..sup.5 -PGF.sub.1, methyl ester, 11,15-diacetate, a compound according to claim 1.

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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Express Scripts

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