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Details for Patent: 4,294,846

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Details for Patent: 4,294,846

Title: Hypocholesteremic fermentation products and products of preparation
Abstract:Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise compounds which have structures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds form a class of highly active hypocholesteremic and hypolipemic medicaments.
Inventor(s): Albers-Schonberg; George (Princeton, NJ), Joshua; Henry (Staten Island, NY), Lopez; Maria B. (Elizabeth, NJ)
Assignee: Merck & Co., Inc. (Rahway, NJ)
Filing Date:May 28, 1980
Application Number:06/154,157
Claims:1. A compound, insubstantially pure form, with structural formula: ##STR6##

2. An antihypercholesterolemic pharmaceutical composition comprising a pharmaceutical carrier and an effective antihypercholesterolemic amount of a compound in substantially pure form, with structural formula: ##STR7##
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