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|Title:||Process for treatment of hyperpigmentary dermatoses|
|Abstract:||There is disclosed a composition for the treatment of acne, hyperpigmentary dermatoses or skin hyperpigmentation which contains dicarboxylic acids containing 7 to 13 carbon atoms or certain derivatives thereof that contain reducing functional group or a salt thereof. There are also disclosed methods for preparing mercapto derivatives of these dicarboxylic acids.|
|Inventor(s):||Nazzaro-Porro; Marcella (Rome, IT)|
|Filing Date:||Dec 01, 1978|
|Claims:||1. A method for the treatment of individuals exhibiting noncancerous or non-precancerous hyperpigmentary dermatoses which comprises administering to said individual a therapeutically effective amount of an active ingredient in a pharmaceutically acceptable carrier until said condition is reduced or its further development is arrested wherein said active ingredient is at least one dicarboxylic acid containing from 7 to 13 carbon atoms or a mono or dimercapto derivative of said acid or a salt thereof. |
2. A method as defined in claim 1 wherein said dicarboxylic acid is selected from the group consisting of pimelic acid, suberic acid, sebacic acid, azelaic acid, 1,9-nonanedicarboxylic acid, 1,10-decanedicarboxylic acid, and 1,11-undecanedicarboxylic acid.
3. A method as defined in claim 1 wherein said individual exhibits a chloasma condition.
4. A method as defined in claim 1 wherein said individual exhibits a poikiloderma of Civatte condition.
5. A method as defined in claim 1 wherein said acid is administered orally.
6. A method as defined in claim 1 wherein said acid is administered by injection.
7. A method as defined in claim 1 wherein said acid is administered topically.
8. A method as defined in claim 1 wherein said dicarboxylic acid is azelaic acid.
9. A method as defined in claim 1 wherein said dicarboxylic acid is 1,10-decanedicarboxylic acid.
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