Deep knowledge on
small-molecule drugs and
the 110,000 global patents
Proactively manage your pharmacy inventory
Drug patents …
… from Kazakhstan to Kalamazoo
Anticipate generic drug launch
Find generic entry opportunities
Manage your formulary budget
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||1,8-Ethano-5-oxo-octa- and -decahydroquinolines and mydriatic compositions thereof|
|Abstract:||Compounds of the general formula: ##STR1## wherein X is selected from the group consisting of oxygen, CH.sub.2 and CH radicals, and when X designates oxygen, R designates alkyl, isoalkyl, aralkyl, and substituted aralkyl groups and when X designates CH.sub.2 then R designates alkyl, phenyl or substituted phenyl group, and A-B is a single bond, and when X designates CH.sub.2 R designates alkyl, phenyl or substituted phenyl groups and A-B is a double bond; and physiologically acceptable salts of these, and mydriatic pharmaceutical compositions containing the same as active ingredient.|
|Inventor(s):||Cohen; Sasson (Tel-Aviv, IL), Fisher; Abraham (Holon, IL)|
|Assignee:||The Purdue Frederick Company (NY)|
|Filing Date:||Nov 17, 1977|
|Claims:||1. A compound of the formula: ##STR8## wherein X is selected from the group consisting of CH.sub.2 and CH, wherein when X is CH.sub.2 then A-B is a single bond and wherein when X is CH then A-B is a double bond and wherein R is selected from the group consisting of lower alkyl, cyclopentyl, cyclohexyl, thienyl, phenyl, methylphenyl, methoxyphenyl, chlorophenyl, trifluoromethylphenyl, aminophenyl, di-loweralkylamino phenyl and benzyl, and physiologically acceptable salts thereof. |
2. A compound of claim 1, 1,8-ethano5-oxo-4-phenyl-1,10,9,8,5,4,3,2-octahydroquinoline and its physiologically acceptable salts.
3. A compound of claim 1, 1,8-ethano-5-oxo-4-phenyl-decahydroquinoline and its physiologically acceptable salts.
4. A compound of claim 1, 1,8-ethano-5-oxo-4-ethyldecahydroquinoline and its physiologically acceptable salts.
5. A pharmaceutical preparation for use as a mydriatic, comprising a mydriatic effective amount of the compound of claim 1 dissolved in a solvent therefor which is pharmaceutically acceptable therefor.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.