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Serving leading biopharmaceutical companies globally:

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Generated: December 13, 2017

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Title: Derivatives of dehydrocyclicimino acids
Abstract:New compounds which have the general formula ##STR1## ARE USEFUL AS HYPOTENSIVE AGENTS.
Inventor(s): Ondetti; Miguel A. (Princeton, NJ), Natarajan; Sehsea I. (Lawrenceville, NJ)
Assignee: E. R. Squibb & Sons, Inc. (Princeton, NJ)
Filing Date:Feb 15, 1978
Application Number:05/878,144
Claims:1. A compound of the formula ##STR12## wherein R and R.sub.2 each is hydrogen or lower alkyl;

R.sub.1 is hydrogen,

m and n each is 0 or 1;

and basic salts thereof.

2. A compound as in claim 1 wherein R and R.sub.2 each is hydrogen or lower alkyl; R.sub.1 is hydrogen and m and n each is 0.

3. A compound as in claim 1 wherein R and R.sub.2 each is hydrogen.

4. A compound as in claim 1 wherein R.sub.1 is hydrogen.

5. A compound as in claim 1 wherein R is hydrogen.

6. A compound as in claim 1 wherein n is 1.

7. A compound as in claim 1 wherein m is 0.

8. A compound as in claim 1 wherein m is 1.

9. A compound as in claim 3 wherein R.sub.1 is hydrogen; m is 0; and n is 1.

10. A compound as in claim 5 wherein R.sub.1 is hydrogen; R.sub.2 is methyl; m is 0; and n is 1.

11. A compound as in claim 5 wherein R.sub.1 is hydrogen; R.sub.2 is methyl; m and n each is 1.

12. A compound as in claim 5 wherein R.sub.1 and R.sub.2 each is hydrogen; m and n each is 1.
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