Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Abstract:||The present invention relates to pyridine derivatives having the formula: ##STR1## in which: R is a radical selected from a phenyl radical mono- and polysubstituted with a group selected from the aryl, carboxy, alkoxycarbonyl, cyano, hydroxymethyl and ethylenedioxy groups; a styryl, thienyl and benzhydryl radical optionally mono- and polysubstituted with a group selected from halogen, lower alkyl, lower alkoxy, aryl, nitro, amino, sulfonylamino, carboxy, alkoxycarbonyl, cyano, hydroxymethyl and methylenedioxy; R.sub.1 and R.sub.2 represent each a group selected from hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, nitro and amino; R.sub.3 represents a group selected from hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, nitro and amino; and n is an integer from 1 to 15, And in which the symbols R.sub.3 may have different meanings in each radical CHR.sub.3 when n is greater than 1, And their inorganic and organic acid addition salts and quaternary ammonium derivatives, particularly 5-o-cyanobenzyl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine maleate. Said derivatives are therapeutically valuable in view of their anti-inflammatory and vasodilator activities and their inhibitor action on blood-platelet aggregation.|
|Inventor(s):||Amselem; Armand (Toulouse, FR)|
|Assignee:||Centre d'Etudes Pour L'Industrie Pharmaceutique (Toulouse, FR)|
|Filing Date:||Jul 09, 1976|
|Claims:||1. 5-o-cyanobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine maleate.|
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.