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|Title:||Synthesis of gon-4-enes|
|Abstract:||1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17.alpha.-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound.|
|Inventor(s):||Hughes; Gordon Alan (Wayne, PA), Smith; Herchel (Wayne, PA)|
|Assignee:||Smith; Herchel (Bryn Mawr, PA)|
|Filing Date:||Jan 15, 1964|
|Claims:||1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17.alpha.-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound. |
2. A composition according to claim 1 wherein said nortestosterone 17-ester is the 17-acetate ester.
3. A therapeutic composition having progestational activity in which the active ingredient is a 17.alpha.-ethynyl-18-methyl-19-nortestosterone 17-aliphatic carboxylic acid ester present in a progestationally effective amount.
4. A therapeutic composition according to claim 3 wherein said ester is 17.alpha.-ethynyl-18-methyl-19-nortestosterone 17-acetate.
5. A method of providing steroid therapy which comprises administering to a subject a therapeutic composition according to claim 3.
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