Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Abstract:||This invention relates to new derivatives of dibenzocycloheptenes and to processes for making them. More particularly, the invention includes 5H-dibenzo[a,d]cycloheptenes and 10,11-dihydro-5H-dibenzo[a,d]cycloheptenes which are substituted at their 5-carbon atom with an aminopropyl or an aminopropylidene radical. The amino entity may be either primary or secondary and if secondary, the substituent may be either a lower alkyl or alkenyl radical having up to 6 carbon atoms, cycloalkyl having up to 8 carbon atoms or an aralkyl radical. The dibenzocycloheptene nucleus may be further substituted. The invention also includes the intermediates used for obtaining these products. Also included are derivatives such as acyl derivatives which yield the active compound under physiological conditions.|
|Inventor(s):||Engelhardt; Edward L. (Gwynedd Valley, PA)|
|Assignee:||Merck & Co., Inc. (Rahway, NJ)|
|Filing Date:||Apr 11, 1975|
|Claims:||1. A compound selected from the group consisting of ##SPC10## |
and the non-toxic acid addition salts thereof; wherein R.degree. is a lower alkyl, R is a lower alkyl, and Y is hydrogen.
3. 10,11-Dihydro-5-(3-methylaminopropyl)-3-methylsulfonyl-5H-dibenzo[a,d]cy cloheptene.
4. 5-(3-Met hylaminopropylidene)-3-methylsulfonyl-5H-dibenzo[a,d]cycloheptene.
5. 10,11-Dihydro-5-(3-methylaminopropylidene)-3-methylsulfonyl-5H- dibenzo[a,d]cycloheptene.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.