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|Title:||Ethers of n-propanol amine|
|Abstract:||Ethers of n-propanolamine, preparation thereof and their use in treatment of cardiovascular conditions.|
|Inventor(s):||Mauvernay; Roland Yves (Riom, FR), Busch; Norbert (Loubeyrat, FR), Moleyre; Jacques (Mozac, FR), Monteil; Andre (Gerzat, FR), Simond; Jacques (Chamalieres, FR)|
|Assignee:||Centre Europeen de Recherches Mauvernay "CERM" (Riom, FR)|
|Filing Date:||Feb 27, 1973|
|Claims:||1. An ether of n-propanolamine having the formula ##EQU10## wherein A is morpholino, pyrrolidino, piperidyl, and di-lower-alkyl amino, R is a straight or branched chain lower alkyl, or benzyl, Ar is aryl and Ar.sup.1 is aryl or pyridyl, and pharmacologically acceptable salts thereof. |
2. The ether of claim 1 in which A is pyrrolidino, R is isobutyl and Ar and Ar.sup.1 are both phenyl, and the hydrochloride thereof.
3. The ether of claim 1 in which A is pyrrolidino, R is isobutyl, Ar is phenyl and Ar.sup.1 is 2-pyridyl, and the acid fumarate thereof.
4. The ether of claim 1 in which A is diethylamino, R is an isobutyl and Ar and Ar.sup.1 are both phenyl, and the acid fumarate thereof.
5. The ether of claim 1 in which A is morpholino, R is isobutyl and Ar and Ar.sup.1 are both phenyl and the acid fumarate thereof.
6. The ether of claim 1 in which A is piperidyl, R is benzyl and Ar and Ar.sup.1 are both phenyl and the hydrochloride thereof.
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