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Generated: October 17, 2017

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Title: Ethers of n-propanol amine
Abstract:Ethers of n-propanolamine, preparation thereof and their use in treatment of cardiovascular conditions.
Inventor(s): Mauvernay; Roland Yves (Riom, FR), Busch; Norbert (Loubeyrat, FR), Moleyre; Jacques (Mozac, FR), Monteil; Andre (Gerzat, FR), Simond; Jacques (Chamalieres, FR)
Assignee: Centre Europeen de Recherches Mauvernay "CERM" (Riom, FR)
Filing Date:Feb 27, 1973
Application Number:05/336,357
Claims:1. An ether of n-propanolamine having the formula ##EQU10## wherein A is morpholino, pyrrolidino, piperidyl, and di-lower-alkyl amino, R is a straight or branched chain lower alkyl, or benzyl, Ar is aryl and Ar.sup.1 is aryl or pyridyl, and pharmacologically acceptable salts thereof.

2. The ether of claim 1 in which A is pyrrolidino, R is isobutyl and Ar and Ar.sup.1 are both phenyl, and the hydrochloride thereof.

3. The ether of claim 1 in which A is pyrrolidino, R is isobutyl, Ar is phenyl and Ar.sup.1 is 2-pyridyl, and the acid fumarate thereof.

4. The ether of claim 1 in which A is diethylamino, R is an isobutyl and Ar and Ar.sup.1 are both phenyl, and the acid fumarate thereof.

5. The ether of claim 1 in which A is morpholino, R is isobutyl and Ar and Ar.sup.1 are both phenyl and the acid fumarate thereof.

6. The ether of claim 1 in which A is piperidyl, R is benzyl and Ar and Ar.sup.1 are both phenyl and the hydrochloride thereof.
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