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Generated: August 21, 2017

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Title: Carbostyril derivatives and process for preparing the same
Abstract:2-Hydroxy-3-alkylaminopropoxycarbostyrils represented by the formula (I) ##SPC1## wherein R represents a straight or branched chain alkyl group having 1 to 4 carbon atoms useful as .beta.-adrenergic blocking agents and a process for preparing the same are disclosed.
Inventor(s): Nakagawa; Kazuyuki (Tokushima, JA), Yoshizaki; Shiro (Komatsushima, JA), Murakami; Nanami (Tokushima, JA), Mori; Hideo (Tokushima, JA)
Assignee: Otsuka Pharmaceutical Co., Ltd. (Tokyo, JA)
Filing Date:Dec 14, 1973
Application Number:05/424,965
Claims:1. A 5- or 8- (2-Hydroxy-3-alkylamino)propoxycarbostyril compound represented by the formula (I): ##SPC4##

wherein R represents a straight or branched alkyl group having 1 to 4 carbon atoms, and the pharmaceutically acceptable acid addition salts thereof.

2. 5-(2-Hydroxy-3-isopropylamino)propoxycarbostyril according to claim 1.

3. 5-(2-Hydroxy-3-tert-butylamino)propoxycarbostyril according to claim 1.

4. 8-(2-Hydroxy-3-tert-butylamino)propoxycarbostyril according to claim 1.

5. 8-(2-Hydroxy-3-isopropylamino)propoxycarbostyril according to claim 1.

6. 8-(2-Hydroxy-3-sec-butylamino)propoxycarbostyril according to claim 1.
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Boehringer Ingelheim
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