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|Title:||Carbostyril derivatives and process for preparing the same|
|Abstract:||2-Hydroxy-3-alkylaminopropoxycarbostyrils represented by the formula (I) ##SPC1## wherein R represents a straight or branched chain alkyl group having 1 to 4 carbon atoms useful as .beta.-adrenergic blocking agents and a process for preparing the same are disclosed.|
|Inventor(s):||Nakagawa; Kazuyuki (Tokushima, JA), Yoshizaki; Shiro (Komatsushima, JA), Murakami; Nanami (Tokushima, JA), Mori; Hideo (Tokushima, JA)|
|Assignee:||Otsuka Pharmaceutical Co., Ltd. (Tokyo, JA)|
|Filing Date:||Dec 14, 1973|
|Claims:||1. A 5- or 8- (2-Hydroxy-3-alkylamino)propoxycarbostyril compound represented by the formula (I): ##SPC4## |
wherein R represents a straight or branched alkyl group having 1 to 4 carbon atoms, and the pharmaceutically acceptable acid addition salts thereof.
2. 5-(2-Hydroxy-3-isopropylamino)propoxycarbostyril according to claim 1.
3. 5-(2-Hydroxy-3-tert-butylamino)propoxycarbostyril according to claim 1.
4. 8-(2-Hydroxy-3-tert-butylamino)propoxycarbostyril according to claim 1.
5. 8-(2-Hydroxy-3-isopropylamino)propoxycarbostyril according to claim 1.
6. 8-(2-Hydroxy-3-sec-butylamino)propoxycarbostyril according to claim 1.
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