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Generated: October 23, 2017

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Title: Asthma treatment by inhalation of micronized N,N-diethyl-4-methyl-1-piperazinecarboxamide pamoate
Abstract:Asthma is effectively treated by inhalation of powder dispensed from an aerosol suspension of powdered N,N-diethyl-4-methyl-1-piperazinecarboxamide pamoate, which is dispersed as a fine powder, essentially below 10 microns in particle size, which gives an improved ratio of absorption in the lungs as compared to systemic absorption.
Inventor(s): Corey, Jr.; Howard Seebree (New City, NY), Barringer; William Charles (Pearl River, NY), Hansen; Lloyd Frank (Campbell Hall, NY)
Assignee: American Cyanamid Company (Stamford, CT)
Filing Date:Jun 27, 1973
Application Number:05/374,174
Claims:1. A method of treating asthma which comprises administering by inhalation to the lungs of an asthamatic individual as a powder predominantly within the particle size range of 0.5 to 10 microns, in a dosage ranging from 1.5 to 90 mg. per day, mono(N,N-diethyl-4-methyl-1-piperazinecarboxamide) pamoate, bis (N,N-diethyl-4-methyl-1-piperazinecarboxamide) pamoate or a mixture thereof.
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