.

Make Better Decisions

  • Analyze global market entry opportunities
  • Uncover prior art in expired and abandoned patents
  • Obtain formulation and manufacturing information

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Medtronic
Citi
Boehringer Ingelheim
US Army
Cerilliant
UBS
QuintilesIMS
Harvard Business School
Daiichi Sankyo
Accenture

Generated: December 17, 2017

DrugPatentWatch Database Preview

Details for Patent: ► Subscribe

« Back to Dashboard

Details for Patent: ► Subscribe

Title: 1-CARBOXAMIDO PYRANO (THIOPYRANO) [3,4-6]INDOLE DERIVATIVES
Abstract:Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus bearing a substituent in position 1, said substituent incorporating an acid, ester or amide function therein, are disclosed. The nucleus is further substituted at position 1 and may be optionally substituted at positions 3, 4, 5, 6, 7, 8, and 9. The derivatives are useful antiinflammatory, analgesic, antibacterial and antifungal agents and methods for their preparation and use are also disclosed.
Inventor(s): Demerson; Christopher A. (St. Laurent, Quebec, CA), Humber; Leslie G. (Dollard des Ormeaux, Quebec, CA), Dobson; Thomas A. (Dollard des Ormeaux, Quebec, CA), Jirkovsky; Ivo L. (Montreal, Quebec, CA)
Assignee: American Home Products Corporation (New York, NY)
Filing Date:Jun 01, 1971
Application Number:05/148,895
Claims:1. A compound of the formula: ##SPC37##

wherein R.sup.1 is lower alkyl having from one to six carbon atoms; R.sup.6 is hydrogen, chlorine, methyl, methoxy or benzyloxy; R.sup.7 is hydrogen or lower alkyl having from one to six carbon atoms; X is oxygen or sulfur; Y is CO, CH.sub.2 CO or CH.sub.2 CH.sub.2 CO; and Z is amino, methylamino, ethylamino, isopropylamino, dimethylamino, diethylamino or phenylamino.

2. A compound of the formula: ##SPC38##

wherein R.sup.1 is lower alkyl having from one to six carbon atoms; Y is CO, CH.sub.2 O, CH.sub.2 CH.sub.2 CO; and Z is amino, methylamino, ethylamino, isopropylamino, dimethylamino, diethylamino or phenylamino.

3. N,N,1-Trimethyl-1,3,4,9-tetrahydropyrano[3,4-b]-indole-1-acetamide, as claimed in claim 2.

4. 1-Methyl-1,3,4,9-tetrahydropyrano[3,4-b]-indole-1-acetamide, as claimed in claim 2.

5. N,1-Dimethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetamide, as claimed in claim 2.

6. N-Phenyl-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetamide, as claimed in claim 2.

7. N,1-Dimethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-propionamide, as claimed in claim 2.

8. 1-Methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-carboxamide, as claimed in claim 2.
« Back to Dashboard

For more information try a trial or see the plans and pricing

Serving leading biopharmaceutical companies globally:

Express Scripts
Federal Trade Commission
Healthtrust
Medtronic
Cerilliant
Teva
Cantor Fitzgerald
Covington
Cipla
UBS

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch:

botpot