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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
US Department of Justice
Boehringer Ingelheim
Queensland Health
Johnson and Johnson

Generated: May 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 3,683,034

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Abstract:A novel process is disclosed for preparing substituted hydroquinone of the formula: ##SPC1## Wherein R is member selected from the group consisting of lower-alkyl, aryl, and lower alkoxy and m is an integer of 1 to 4; by reductive hydrolysis of the corresponding nitrosophenol. 7 Claims, No Drawings
Inventor(s): William Von E. Doering (Cambridge, MA), William J. Farrissey, Jr. (Northford, CT), Floro F. Frulla (Wallingford, CT), Durvasula V. Rao (Hamden, CT)
Assignee: The Upjohn Company, Kalamazoo, MI (N/A)
Filing Date:Apr 16, 1970
Application Number:05/029,279
Claims:1. A process for preparing a substituted hydroquinone of the formula: ##SPC5## wherein R is a member selected from the group consisting of lower alkyl, aryl and lower-alkoxy and m is an integer of 1 to 4; which process comprises heating the corresponding p-nitrosophenol to a temperature of about 60.degree. to 120.degree.C, in an 0.1 N to 6 N aqueous solution of a mineral acid selected from the group consisting of sulfuric, phosphoric and hydrochloric acid, and in the presence of hydrogen and from about 1 percent to about 5 percent by weight of said p-nitrosophenol, of a noble metal hydrogenation catalyst; the concentration of said p-nitrosophenol in

2. The process of claim 1, wherein said hydrogenation catalyst is platinum

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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
Express Scripts
US Army
US Department of Justice

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