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Generated: July 23, 2017
| Title: | 2-FORMYL-(6-METHOXY-2-NAPHTHYL) ACETIC ACID |
| Abstract: | 2-(6-Methoxy-2-naphthyl)propionic acid is prepared by reacting a compound having the formula with hydrogen in the presence of a hydrogenation catalyst until a 2-(6-methoxy-2-naphthyl)propionate is formed, and hydrolyzing the ester group of the propionate. In the formula, R.sup.1 is an alkyl, cycloalkyl, aralkyl or alkenyl group and R.sup.2 is --OR.sup.3, --SR.sup.3, wherein R.sup.3, R.sup.5 and R.sup.6 each is alkyl or cycloalkyl; R.sup.4 is alkyl, cycloalkyl, aryl or aralkyl; and R.sup.5 and R.sup.6 together can be ethylene or a polymethylene group having from three to seven carbons. The product has anti-inflammatory, analgesic, and anti-pyretic activities. |
| Inventor(s): | Nelson; Peter H. (Los Altos, CA) |
| Assignee: | Syntex Corporation (Panama, PM) |
| Filing Date: | Sep 30, 1969 |
| Application Number: | 04/862,500 |
| Claims: | 1. A compound selected from the group consisting of 2-formyl-2-(6-methoxy-2-naphthyl acetic acid and the alkyl, cycloalkyl, aralkyl and alkenyl esters thereof. |
Serving 500+ biopharmaceutical companies globally:
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