Generated: May 28, 2017
|Abstract:||L-.alpha.-acylhydrazino-.beta.-phenyl-propionitrile compounds useful as intermediates in the production of L-.alpha.-hydrazino-.beta.-phenyl-propionic acids. Also included are processes for preparing the compounds of this invention by aminating L-.alpha.-acylamido-.beta.-phenyl-propionitrile and processes for hydrolyzing the compounds of this invention to form L-.alpha.-hydrazino-.beta.-phenyl-propionic acid compounds.|
|Inventor(s):||Sletzinger; Meyer (North Plainfield, NJ), Karady; Sandor (Elizabeth, NJ), Ly; Manuel G. (New Brunswick, NJ), Pines; Seemon H. (Murray Hill, NJ)|
|Assignee:||Merck & Co., Inc. (Rahway, NJ)|
|Filing Date:||Feb 24, 1970|
|Claims:||1. A compound of the formula: |
R and R.sub.1 each may be loweralkoxy, phenyloxy, benzyloxy or hydroxy;
R.sub.2 is hydrogen or loweralkyl;
R.sub.3 is --CN; and
R.sub.4 is loweralkanoyl.
2. A compound as in claim 1 wherein R and R.sub.1 are loweralkoxy, R.sub.2 is loweralkyl, R.sub.3 is -CN and R.sub.4 is acetyl.
3. A compound as in claim 1 wherein R is hydroxy, R.sub.1 is loweralkoxy, R.sub.2 is loweralkyl, R.sub.3 is --CN and R.sub.4 is acetyl.
4. A compound as in claim 1 wherein R and R.sub.1 are hydroxy, R.sub.2 is loweralkyl, R.sub.3 is --CN and R.sub.4 is acetyl.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.