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Claims for Patent: 8,685,957

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Claims for Patent: 8,685,957

Title:Tazobactam arginine compositions
Abstract: This disclosure provides compositions containing solid forms of tazobactam arginine, and methods of manufacturing and using these compositions.
Inventor(s): Lai; Jan-Ji (Westborough, MA), Gu; Jian-Qiao (Lexington, MA), Pathare; Pradip M. (Lexington, MA), Jurkauskas; Valdas (Cambridge, MA), Terracciano; Joseph (Concord, MA), Damour; Nicole Miller (Belmost, MA)
Assignee: Cubist Pharmaceuticals, Inc. (Lexington, MA)
Application Number:13/828,534
Patent Claims: 1. A method for the treatment of bacterial infections in a mammal, comprising administering to said mammal a therapeutically effective amount of a pharmaceutical composition comprising tazobactam arginine polymorph Ia.

2. The method of claim 1 wherein the mammal is human.

3. A method for the treatment of bacterial infections in a mammal, comprising administering to said mammal a therapeutically effective amount of a pharmaceutical composition comprising a beta-lactam compound and tazobactam arginine polymorph Ia.

4. The method of claim 3 wherein the mammal is a human.

5. A pharmaceutical composition comprising tazobactam arginine polymorph Ia and one or more beta-lactam compounds, and a pharmaceutically acceptable carrier or diluent.

6. A pharmaceutical composition prepared by a method comprising the step of combining tazobactam arginine polymorph Ia and a beta-lactam compound.
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