DrugPatentWatch Database Preview
« Back to Dashboard
Summary for Patent: 8,475,839
|Title:||Solid dosage forms of valsartan, amlodipine and hydrochlorothiazide and method of making the same|
|Abstract:||Monolayer, bilayer and trilayer solid dosage forms of a combination of valsartan, amlodipine and hydrochlorothiazide are made.|
|Inventor(s):||Cao; Yu (Parsippany, NJ), Joshi; Yatindra (Princeton, NJ), Li; Ping (Basking Ridge, NJ), Pudipeddi; Madhusudhan (Mumbai, IN), Royce; Alan E (Saylorsburg, PA), Wagner; Robert F (Hillsborough, NJ), Zhu; Jiahao (Whippany, NJ)|
|Assignee:||Novartis AG (Basel, CH)|
1. A solid dosage form comprising: valsartan; amlodipine; hydrochlorothiazide; and pharmaceutically acceptable additives suitable for the preparation of solid dosage
forms of valsartan, wherein the solid dosage form of valsartan/hydrochlorothiazide/amlodipine is selected from 160 mg/12.5 mg/5 mg, 160 mg/12.5 mg/10 mg, 160 mg/25 mg/10 mg, 160 mg/25 mg/5 mg and 320 mg/25 mg/10 mg, said solid dosage either in the form
of a monolayer tablet or a bilayer tablet.
2. The solid dosage form of claim 1, wherein the amlodipine is provided in the form of amlodipine besylate.
3. The solid dosage form of claim 1, wherein the solid dosage form takes the form of a monolayer tablet.
4. The solid dosage form of claim 1, wherein the solid dosage form takes the form of a bilayer tablet.
5. The solid dosage form of claim 4, wherein the bilayer tablet has the valsartan and the hydrochlorothiazide in a first layer and the amlodipine in a second layer.
6. The solid dosage form of claim 4, wherein the bilayer tablet has the valsartan in a first layer and the amlodipine and the hydrochlorothiazide in a second layer.
7. The solid dosage form of claim 1, wherein the pharmaceutically acceptable additives are selected from the group consisting of diluents, disintegrants, glidants, lubricants, binders, colorants and combinations thereof.
For more information try a trial or see the plans and pricing
Serving hundreds of leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.