You are 3 steps away
from making better decisions

Serving leading biopharmaceutical companies globally:

Harvard Business School
Baxter
Johnson and Johnson
Merck
Express Scripts
Boehringer Ingelheim

Last Updated: September 18, 2020

DrugPatentWatch Database Preview

Claims for Patent: 8,299,298

➤ Get the DrugPatentWatch Daily Briefing
» See Plans and Pricing

« Back to Dashboard

Summary for Patent: 8,299,298
Title:Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
Abstract: The present invention discloses pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. A manufacturing and quality control process for making a pharmaceutical-grade ferric citrate that consistently complies with the established Manufacture Release Specification is also disclosed. The pharmaceutical-grade ferric organic compounds are suitable for treating disorders characterized by elevated serum phosphate levels.
Inventor(s): Chan; Keith (Rockville, MD), Town; Winston (Hong Kong, CN)
Assignee: Globoasia, LLC (Rockville, MD)
Application Number:13/289,048
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,299,298
Patent Claims: 1. A pharmaceutical composition comprising ferric citrate having a BET active surface area of at least 16 sq. m/g and a pharmaceutically suitable carrier, wherein the ferric citrate is present in an amount effective to reduce serum phosphate levels.

2. The pharmaceutical composition of claim 1, wherein the ferric citrate has an intrinsic dissolution rate of 1.88-4.0 mg/cm.sup.2/min.

3. The pharmaceutical composition of claim 1, wherein the effective amount of ferric citrate is from 2 grams per day-30 grams per day.

4. The pharmaceutical composition of claim 1, wherein the effective amount of ferric citrate is from 4 grams per day-15 grams per day.

5. The pharmaceutical composition of claim 1, wherein the effective amount of ferric citrate is from 2 grams per day-12 grams per day.

6. The pharmaceutical composition of claim 1, wherein the effective amount of ferric citrate is selected from 2 grams per day, 4 grams per day and 6 grams per day.

7. The pharmaceutical composition of claim 1, wherein the effective amount of ferric citrate is 1 gram per day.

8. The pharmaceutical composition of claim 1, wherein the effective amount of ferric citrate is 500 mg per unit dosage form.

9. A pharmaceutical composition comprising 500 mg of ferric citrate having a BET active surface area of at least 16 sq. m/g, and a pharmaceutically suitable carrier, wherein the pharmaceutical composition is in a capsule dosage form.

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Express Scripts
Harvard Business School
Boehringer Ingelheim
Mallinckrodt
McKesson
Johnson and Johnson

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.