|Title:||Colchicine compositions and methods|
|Abstract:|| Stable ultrapure colchicine compositions comprising ultrapure colchicine and a pharmaceutically acceptable excipient are described. The compositions can be tablets. Methods for preparing such compositions and methods of use are also disclosed. Methods of treating gout flares with colchicine compositions are also disclosed.|
|Inventor(s):|| Davis; Matthew W. (Erwinna, PA) |
|Assignee:|| Mutual Pharmaceutical Company, Inc. (Philadelphia, PA) |
1. A method of treating a gout flare with colchicine in a patient undergoing colchicine prophylactic treatment of gout flares, consisting of administering to a patient having a gout
flare while undergoing prophylactic treatment of gout flares 1.2 mgA oral colchicine at the onset of the acute gout flare, followed by 0.6 mgA oral colchicine about one hour later; and after waiting 12 hrs, continuing prophylactic treatment consisting
of 0.6 mgA or 1.2 mgA oral colchicine daily.