Generated: May 25, 2017
|Title:||Methods of treating allergic reactions using an anhydrous form of antihistaminic piperidine derivatives|
|Abstract:||The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas ##STR00001## which are useful as antihistamines, antiallergic agents and bronchodilators.|
|Inventor(s):||McCarty; Frederick J. (Hilton Head Island, SC), Carr; Albert A. (Cincinnati, OH)|
|Assignee:||Aventis Holdings, Inc. (Bridgewater, NJ)|
|Patent Claims:||1. A method of treating an allergic reaction in a patient in need thereof comprising administering to said patient a solid unit dosage form comprising an effective amount of 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-.alpha.,.a- lpha.-dimethylbenzeneacetic acid hydrochloride comprising Form I anhydrous 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-.alpha.,.a- lpha.-dimethylbenzeneacetic acid hydrochloride.|
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