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Serving leading biopharmaceutical companies globally:

Novartis
Citi
Federal Trade Commission
Chubb
Johnson and Johnson
Boehringer Ingelheim
McKesson
Moodys
AstraZeneca
Cipla

Generated: February 19, 2018

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Claims for Patent: 7,230,012

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Summary for Patent: 7,230,012
Title:Pharmaceutical compositions and dosage forms of thalidomide
Abstract:Pharmaceutical compositions and single unit dosage forms of thalidomide and pharmaceutically acceptable prodrugs, salts, solvates, hydrates, or clathrates are disclosed. Also disclosed are methods of treating and preventing diseases and conditions such as, but not limited to, leprosy, chronic graft-vs-host disease, rheumatoid arthritis, sarcoidosis, an inflammatory condition, inflammatory bowel disease, and cancer using the novel dosage forms disclosed herein.
Inventor(s): D'Angio; Paul (Basking Ridge, NJ), McCarty; John (Miami Springs, FL)
Assignee: Celgene Corporation (Summit, NJ)
Application Number:10/608,077
Patent Claims: 1. A single unit dosage form in the form of a size 4 capsule comprising a uniform admixture of 50 mg thalidomide and 74 mg of pregelatinized corn starch.

2. The dosage form of claim 1, which further comprises magnesium stearate.

3. The dosage form of claim 2, wherein the magnesium stearate is present in an amount of 1 mg.

4. The dosage form of claim 3, the contents of which weighs 125 mg.

5. A single unit dosage form in the form of a size 2 capsule, the contents of which weighs 250 mg, and comprising 100 mg of thalidomide and pregelatinized corn starch.

6. The dosage form of claim 5, which further comprises magnesium stearate.

7. A single unit dosage form in the form of a size 0 capsule comprising a uniform admixture of 200 mg of thalidomide and 297.5 mg of pregelatinized corn starch.

8. The dosage form of claim 7, which further comprises magnesium stearate.

9. The dosage form of claim 8, wherein the magnesium stearate is present in an amount of 2.5 mg.

10. The dosage form of claim 9, the contents of which weighs 500 mg.

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Mallinckrodt
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Deloitte

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