Claims for Patent: 6,197,819

Summary for Patent: 6,197,819

Title:	Gamma amino butyric acid analogs and optical isomers
Abstract:	A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
Inventor(s):	Silverman; Richard B. (Morton Grove, IL), Andruszkiewicz; Ryszard (Sopot, PL)
Assignee:	Northwestern University (Evanston, IL)
Application Number:	08/420,905
Patent Claims:	1. A compound of the formula S-(+)-4-amino-3-(2-methylpropyl) butanoic acid as a single optical isomer. 2. 4-amino-3-(2-methylpropyl) butanoic acid, or a pharmaceutically acceptable salt thereof. 3. A pharmaceutically acceptable salt of S-(+)-(4)-amino-3-(2-methylpropyl) butanoic acid, said salt being present as a single optical isomer. 4. A pharmaceutical composition comprising a compound any one of claims 1 or 3, together with a pharmaceutically acceptable carrier.