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|Title:||Method for ameliorating muscle weakness/wasting in a patient infected with human immunodeficiency virus-type 1|
|Abstract:||A method for attenuating the HIV-associated myopathy and muscle wasting associated with infection by human immunodeficiency virus-Type 1. Administration of oxandrolone in a daily dosage of about 2.5 to about 20 milligrams is described.|
|Inventor(s):||Berger; Joseph R. (Miami, FL)|
|Assignee:||BTG Pharmaceuticals Corp. (Iselin, NJ)|
1. A method for ameliorating HIV-associated myopathy and muscle weakness in an AIDS patient which comprises orally administering oxandrolone to the AIDS patient in a daily
dosage of between about 2.5 to about 7.5 milligrams.
2. The method in accordance with claim 1 wherein the daily dosage of the oxandrolone is about 7.5 milligrams.
3. The method in accordance with claim 1 wherein the oxandrolone is administered to said patient as a unit dose of about 1 to about 2.5 milligrams three times per day at about eight-hour intervals.
4. The method in accordance with claim 1 wherein the oxandrolone is administered in the form of a tablet.
5. The method in accordance with claim 1 wherein administration is continued over a period of about 2 weeks.
6. The method in accordance with claim 1 wherein administration is continued over a period of about 2 weeks.
7. The method in accordance with claim 3 wherein administration is continued over a period of about 2 weeks.
8. A method for ameliorating HIV-associated myopathy and muscle wasting in an AIDS patient which comprises orally administering a therapeutically effective amount of oxandrolone to the AIDS patient daily for a time period of about 2 weeks.
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