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Claims for Patent: 6,090,799

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Claims for Patent: 6,090,799

Title: Method for ameliorating muscle weakness/wasting in a patient infected with human immunodeficiency virus-type 1
Abstract:A method for attenuating the HIV-associated myopathy and muscle wasting associated with infection by human immunodeficiency virus-Type 1. Administration of oxandrolone in a daily dosage of about 2.5 to about 20 milligrams is described.
Inventor(s): Berger; Joseph R. (Miami, FL)
Assignee: BTG Pharmaceuticals Corp. (Iselin, NJ)
Application Number:08/244,988
Patent Claims: 1. A method for ameliorating HIV-associated myopathy and muscle weakness in an AIDS patient which comprises orally administering oxandrolone to the AIDS patient in a daily dosage of between about 2.5 to about 7.5 milligrams.

2. The method in accordance with claim 1 wherein the daily dosage of the oxandrolone is about 7.5 milligrams.

3. The method in accordance with claim 1 wherein the oxandrolone is administered to said patient as a unit dose of about 1 to about 2.5 milligrams three times per day at about eight-hour intervals.

4. The method in accordance with claim 1 wherein the oxandrolone is administered in the form of a tablet.

5. The method in accordance with claim 1 wherein administration is continued over a period of about 2 weeks.

6. The method in accordance with claim 1 wherein administration is continued over a period of about 2 weeks.

7. The method in accordance with claim 3 wherein administration is continued over a period of about 2 weeks.

8. A method for ameliorating HIV-associated myopathy and muscle wasting in an AIDS patient which comprises orally administering a therapeutically effective amount of oxandrolone to the AIDS patient daily for a time period of about 2 weeks.
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