.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 5,962,468

« Back to Dashboard

Claims for Patent: 5,962,468

Title: 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1- cyclopropyl-6-fluoro-4-oxo-1, 4-dihydro-1, 8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
Abstract:The present invention relates to a novel quinolone compound having an excellent antibacterial activity. More specifically, the present invention relates to 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4 -oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid represent by the following formula: ##STR1## or its isomer.
Inventor(s): Hong; Chang Yong (Daejeon, KR), Kim; Young Kwan (Daejeon, KR), Kim; Se Ho (Daejeon, KR), Chang; Jay Hyok (Daejeon, KR), Choi; Hoon (Daejeon, KR), Nam; Do Hyun (Daejeon, KR), Kim; Ae Ri (Daejeon, KR), Lee; Jin Hwa (Daejeon, KR), Park; Ki Sook (Daejeon, KR)
Assignee: LG Chemical Ltd. (Seoul, KR)
Application Number:09/188,063
Patent Claims: 1. A method for prophylaxis or treatment of bacterial infections in a warm blooded animal, comprising administering an effective amount of the compound 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4 -oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid of the following formula: ##STR269## or a pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, or isomer thereof.

2. The method according to claim 1 wherein the compound is in the form of Z-isomer.

3. The method according to claim 1 wherein the compound is administered once a day.

4. The method according to claim 1 wherein the warm blooded mammal is a human being.

5. A method for prophylaxis or treatment of bacterial infections in a warm blooded animal, comprising administering 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4 -oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate or a hydrate thereof of the following formula: ##STR270## in which n is 0, 1, 1.5, 2.5, 3, 3.5 or 4, or an isomer thereof.

6. The method according to claim 5 wherein the compound is in the form of Z-isomer.

7. The method according to claim 5 wherein n is 3.

8. The method according to claim 5 wherein the compound has a moisture content of from 9 to 11% by weight.

9. The method according to claim 5 wherein n is 1.5.

10. The method according to claim 5 wherein the compound has a moisture content of from 4 to 6% by weight.

11. The method according to claim 5 wherein the compound is administered once a day.

12. The method according to claim 5 wherein the warm blooded animal is a human being.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc