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Last Updated: April 20, 2024

Claims for Patent: 5,872,147


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Summary for Patent: 5,872,147
Title: Use of oxandrolone in the treatment of chronic obstructive pulmonary disease
Abstract:The subject invention provides a method of treating a symptom associated with chronic obstructive pulmonary disease in a patient suffering from chronic obstructive pulmonary disease which comprises administering a therapeutically effective amount of an oxandrolone to the patient. The subject invention further provides a method of improving functional capacity and/or pulmonary function in a patient suffering from chronic obstructive pulmonary disease which comprises administering a therapeutically effective amount of an oxandrolone to the patient.
Inventor(s): Bowen; Robert E. (Martinsburg, WV)
Assignee: Bio-Technology General Corp. (Iselin, NJ)
Application Number:08/986,015
Patent Claims: 1. A method of treating a symptom associated with chronic obstructive pulmonary disease in a patient suffering from chronic obstructive pulmonary disease which comprises administering a therapeutically effective amount of an oxandrolone to the patient.

2. A method according to claim 1, wherein the symptom is cachexia, muscle wasting or involuntary weight loss.

3. A method of improving pulmonary function in a patient suffering from chronic obstructive pulmonary disease which comprises administering a therapeutically effective amount of an oxandrolone to the patient.

4. A method of improving functional capacity in a patient suffering from chronic obstructive pulmonary disease which comprises administering a therapeutically effective amount of an oxandrolone to the patient.

5. A method according to claims 1, 3, or 4 wherein the amount of the oxandrolone is about 1-100 mg/day.

6. A method according to claim 5 wherein the amount of the oxandrolone is about 10-20 mg/day.

7. A method according to claim 5 wherein the amount of the oxandrolone is about 0.2 mg/kg/day.

8. A method according to claims 1, 3 or 4 wherein the oxandrolone is administered orally.

9. A method according to claims 1, 3, or 4 wherein the oxandrolone is injected.

10. A method according to claims 1, 3, or 4 wherein the oxandrolone is in a solid dosage form.

11. A method according to claims 1, 3, or 4 wherein the oxandrolone is in a liquid dosage form.

12. A method according to claims 1, 3, or 4 wherein the oxandrolone is in a sustained-release formulation.

13. A method of improving pulmonary function in a patient suffering from adult respiratory distress syndrome which comprises administering a therapeutically effective amount of an oxandrolone to the patient.

14. A method of improving functional capacity in a patient suffering from adult respiratory distress syndrome which comprises administering a therapeutically effective amount of an oxandrolone to the patient.

15. A method according to claims 1, 3, 4, 13 or 14, wherein the oxandrolone is 17.alpha.-methyl-17.beta.-hydroxy-2-oxa-5.alpha.-androstan-3-one.

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