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Serving leading biopharmaceutical companies globally:

Queensland Health
Fuji
UBS
US Army
Fish and Richardson
Cerilliant
Argus Health
Novartis
Johnson and Johnson
Citi

Generated: February 22, 2018

DrugPatentWatch Database Preview

Claims for Patent: 5,856,336

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Summary for Patent: 5,856,336
Title: Quinoline type mevalonolactones
Abstract:A compound of the formula ##STR1## Z=--CH(OH)--CH.sub.2 --CH(OH)--CH.sub.2 --COO.1/2Ca have HMG--CoA inhibiting effects, making them useful as inhibitors of cholesterol biosynthesis. The compound may be prepared as a pharmaceutical for reducing hyperlipidemia, hyperlipoproteinemia or atherosclerosis.
Inventor(s): Fujikawa; Yoshihiro (Funabashi, JP), Suzuki; Mikio (Funabashi, JP), Iwasaki; Hiroshi (Funabashi, JP), Sakashita; Mitsuaki (Shiraoka-machi, JP), Kitahara; Masaki (Shiraoka-machi, JP)
Assignee: Nissan Chemical Industries Ltd. (Tokyo, JP)
Application Number:07/883,398
Patent Claims: 1. A compound of the formula, ##STR16## Z=--CH(OH)--CH.sub.2 --CH(OH)--CH.sub.2 --COO.1/2Ca.

2. A method for reducing hyperlipidemia, hyperlipoproteinemia or atherosclerosis, which comprises administering an effective amount of the compound of formula A as defined in claim 1.

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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Healthtrust
Johnson and Johnson
McKesson
Cipla
Chubb
Fish and Richardson
Cerilliant
Daiichi Sankyo

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