DrugPatentWatch Database Preview
« Back to Dashboard
Summary for Patent: 4,812,561
|Title:||Crystalline hydrate of oral cephalosporin and its composition|
|Abstract:||An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4 -carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.|
|Inventor(s):||Hamashima; Yoshio (Kyoto, JP), Minami; Kyoji (Nara, JP), Kawata; Kyozo (Osaka, JP), Sakamoto; Teruo (Osaka, JP), Takeda; Toyohiko (Hyogo, JP), Suzuki; Yusuke (Osaka, JP), Tujikawa; Masanori (Nara, JP)|
|Assignee:||Shionogi & Co., Ltd. (Osaka, JP)|
1. A crystalline hydrate of 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4 -carboxylic acid having the X-ray diffraction pattern as follows:
2. A hydrate as claimed in claim 1 that contains 7 to 14% of crystal water.
3. A hydrate as claimed in claim 1 that is dihydrate.
4. A hydrate as claimed in claim 1 that is trihydrate.
For more information try a trial or see the plans and pricing
Serving hundreds of leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.