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Serving leading biopharmaceutical companies globally:

Mallinckrodt
Deloitte
Johnson and Johnson
Express Scripts
McKinsey
Merck
Baxter
Queensland Health
Farmers Insurance
Colorcon

Generated: October 21, 2017

DrugPatentWatch Database Preview

Claims for Patent: 4,687,777

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Claims for Patent: 4,687,777

Title: Thiazolidinedione derivatives, useful as antidiabetic agents
Abstract:Thiazolidinedione derivatives of the formula: ##STR1## and pharmacologically acceptable salts thereof are novel compounds, which exhibit in mammals blood sugar- and lipid-lowering activity, and are of value as a therapeutic agent for treatment of diabetes and hyperlipemia.
Inventor(s): Meguro; Kanji (Nishinomiya, JP), Fujita; Takeshi (Takarazuka, JP)
Assignee: Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:06/820,390
Patent Claims: 1. A compound of the formula: ##STR15## or a pharmacologically acceptable salt thereof.

2. A compound as claimed in claim 1, wherein the compound is 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione.

3. A compound as claimed in claim 1, wherein the compound is sodium salt of 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzylbenzyl}-2,4-thiazolidinedione.

4. A compound as claimed in claim 1, wherein the compound is 5-{4-[2-(6-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione.

5. An antidiabetic composition which consists essentially of a compound of the formula: ##STR16## or a pharmacologically acceptable salt thereof, in association with a pharmacologically acceptable carrier, excipient or diluent.
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Serving leading biopharmaceutical companies globally:

Dow
Medtronic
Farmers Insurance
Accenture
Mallinckrodt
Citi
Covington
Queensland Health
Merck
Novartis

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