Claims for Patent: 4,687,777

Summary for Patent: 4,687,777

Title:	Thiazolidinedione derivatives, useful as antidiabetic agents
Abstract:	Thiazolidinedione derivatives of the formula: ##STR1## and pharmacologically acceptable salts thereof are novel compounds, which exhibit in mammals blood sugar- and lipid-lowering activity, and are of value as a therapeutic agent for treatment of diabetes and hyperlipemia.
Inventor(s):	Meguro; Kanji (Nishinomiya, JP), Fujita; Takeshi (Takarazuka, JP)
Assignee:	Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:	06/820,390
Patent Claims:	1. A compound of the formula: ##STR15## or a pharmacologically acceptable salt thereof. 2. A compound as claimed in claim 1, wherein the compound is 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione. 3. A compound as claimed in claim 1, wherein the compound is sodium salt of 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzylbenzyl}-2,4-thiazolidinedione. 4. A compound as claimed in claim 1, wherein the compound is 5-{4-[2-(6-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione. 5. An antidiabetic composition which consists essentially of a compound of the formula: ##STR16## or a pharmacologically acceptable salt thereof, in association with a pharmacologically acceptable carrier, excipient or diluent.