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Claims for Patent: 4,589,402

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Claims for Patent: 4,589,402

Title: Method of in vitro fertilization
Abstract:A method of in vitro fertilization therapy, which includes means for inducing ovulation by administering an exogenous human menopausal gonadotropin preparation and human chorionic gonadotropin, harvesting the mature follicles, combining the ovum with spermatazoa in vitro and transferring the conceptus into the uterus is improved by employing FSH as the exogenous human menopausal gonadotropin in the absence of exogenous LH.
Inventor(s): Hodgen; Gary D. (Potomac, MD), Jones, Jr.; Howard W. (Norfolk, VA), Jones; Georgeanna S. (Norfolk, VA)
Assignee: SErono Laboratories, Inc. (Randolph, MA)
Application Number:06/634,697
Patent Claims: 1. In a method of in vitro fertilization which comprises the initial steps of inducing follicular maturation by administering exogeneous human menopausal gonadotropins to a female, inducing ovulation, harvesting the eggs from large ovarian follicles, combining each ovum with spermatozoa in vitro and transferring the conceptus into the uterus, the improvement which consists of employing FSH alone as said exogeneous human menopausal gonadotropin without the presence of exogeneous LH.

2. The method of claim 1, wherein the daily amount of FSH is about 5-10 IU/kg.

3. The method of claim 1, wherein an ovulatory inducing amount of hCG is administered.
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