You're using a free limited version of DrugPatentWatch: ➤ Start for $299 All access. No Commitment.

Last Updated: December 15, 2025

Claims for Patent: 11,027,072

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 11,027,072

Title:	Emergency devices
Abstract:	Described herein are syringe devices comprising a syringe including a therapeutic dose of at least one drug to be used in a drug or substance overdose. Also provided herein are compositions and methods of treating opioid overdose using high dose naloxone.
Inventor(s):	Mark J. Flather, Karen K. Daniels, Thomas Moll, Ronald B. Moss, Dennis J. Carlo
Assignee:	Zmi Pharma Inc
Application Number:	US16/592,319
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 11,027,072
Patent Claims:	1. A high dose naloxone composition including naloxone at a dose greater than or equal to about 5 mg configured for administration, wherein Cmax is between 15 ng/mL to 24 ng/mL and the administration is an injection. 2. The high dose naloxone composition of claim 1, wherein the dose is greater than about 10 mg. 3. The high dose naloxone composition of claim 1, including naloxone hydrochloride at a dose of 5 mg/0.5 mL. 4. The high dose naloxone composition of claim 3, wherein the composition is configured for a single administration. 5. The high dose naloxone composition of claim 4, wherein the administration is using an injection device. 6. The high dose naloxone composition of claim 1, wherein the composition is aqueous. 7. The high dose naloxone composition of claim 1, wherein the Cmax is 15.8 ng/mL. 8. The high dose naloxone composition of claim 1, wherein the Cmax is 17.2 ng/mL. 9. A high dose naloxone composition including naloxone at a dose greater than about 5 mg configured for administration, wherein the AUC0-0.04 h is between 0.01 hng/mL and 0.1 hng/mL and the administration is an injection. 10. The high dose naloxone composition of claim 9, including naloxone hydrochloride at a dose of 5 mg/0.5 mL. 11. The high dose naloxone composition of claim 10, wherein the composition is configured for a single administration. 12. The high dose naloxone composition of claim 11, wherein the administration is using an injection device. 13. The high dose naloxone composition of claim 9, wherein the AUC0-0.04 h is 0.0129 hng/mL. 14. A high dose naloxone composition including naloxone at a dose greater than or equal to about 5 mg configured for administration, wherein the AUC0-0.08 h is between 0.05 hng/mL to 0.2 hng/mL and the administration is an injection. 15. The high dose naloxone composition of claim 14, including naloxone hydrochloride at a dose of 5 mg/0.5 mL. 16. The high dose naloxone composition of claim 15, wherein the composition is configured for a single administration. 17. The high dose naloxone composition of claim 16, wherein the administration is using an injection device. 18. The high dose naloxone composition of claim 14, wherein the AUC0-0.08 h is 0.0782 hng/mL.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.