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Last Updated: April 25, 2024

Claims for Patent: 10,265,404


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Summary for Patent: 10,265,404
Title:Compositions, gels and foams with rheology modulators and uses thereof
Abstract: The present disclosure relates generally to compositions for cosmetic or pharmaceutical application. The compositions include a carrier and rheology modulators.
Inventor(s): Tamarkin; Dov (Maccabim, IL), Gazal; Elana (Rehovot, IL), Hazot; Yohan (Rehovot, IL), Schuz; David (Gimzu, IL), Papiashvili; Irakliy (Ashkelon, IL)
Assignee: Foamix Pharmaceuticals Ltd. (Rehovot, IL)
Application Number:14/078,746
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,265,404
Patent Claims: 1. An oleaginous foam composition comprising: a) a combination of at least one fatty alcohol and at least one wax; or a combination of at least one fatty alcohol, at least one fatty acid, and at least one wax; b) at least one hydrophobic solvent; and c) a minocycline at a concentration between about 1% and about 4% by weight of the composition; wherein the composition is free of surfactant; wherein the composition is essentially waterless; wherein the ratio of (1) fatty alcohol to wax or (2) fatty alcohol and fatty acid to wax is between about 1:3 and about 3:1; and wherein the wax comprises a mixture of beeswax and hydrogenated castor oil.

2. The composition of claim 1, wherein the minocycline is present in a free base form, a hydrate form, a salt form, or a complex form.

3. The composition of claim 1, further comprising a tetracycline, an oxytetracycline, a demeclocycline, a doxycycline, a lymecycline, a meclocycline, a methacycline, a rolitetracycline, a chlorotetracycline, a tigecycline, or a mixture of two or more thereof.

4. The composition of claim 1, further comprising a doxycycline.

5. The composition of claim 1, wherein the concentration of the minocycline is about 4% by weight of the composition.

6. The composition of claim 1, wherein the concentration of the minocycline is about 1% by weight of the composition.

7. The composition of claim 1, wherein the at least one fatty alcohol comprises 14 carbon atoms in its backbone.

8. The composition of claim 1, wherein the fatty alcohol comprises stearyl alcohol, cetostearyl alcohol, behenyl alcohol, and/or myristyl alcohol.

9. The composition of claim 1, wherein the at least one fatty alcohol is present at a concentration from about 0.1% to about 20% by weight of the composition.

10. The composition of claim 1, wherein the at least one wax and/or the at least one fatty acid is present at a concentration from about 0.1% to about 20% by weight of the composition.

11. The composition of claim 1, wherein the hydrophobic solvent comprises soybean oil, coconut oil, cyclomethicone, and/or mineral oil.

12. The composition of claim 1, wherein the hydrophobic solvent is present at a concentration from about 60% to about 95% by weight of the composition.

13. The composition of claim 1, further comprising a retinoid.

14. The composition of claim 13, wherein the retinoid comprises tazarotene, adapalene, and/or isotretinoin.

15. The composition of claim 1, further comprising a silicon dioxide.

16. The composition of claim 1, further comprising a benzoyl peroxide.

17. The composition of claim 1, wherein the wax comprises a mixture of beeswax and hydrogenated castor oil at a ratio of about 1:1.

18. The composition of claim 1, wherein the concentration of the minocycline is about 3% by weight of the composition.

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