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Generated: October 21, 2018

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Tirofiban hydrochloride - Generic Drug Details

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What are the generic sources for tirofiban hydrochloride and what is the scope of tirofiban hydrochloride freedom to operate?

Tirofiban hydrochloride is the generic ingredient in one branded drug marketed by Medicure and is included in two NDAs. There are two patents protecting this compound. Additional information is available in the individual branded drug profile pages.

There are four drug master file entries for tirofiban hydrochloride. One supplier is listed for this compound.

Pharmacology for tirofiban hydrochloride
Synonyms for tirofiban hydrochloride
(2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid
(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid
(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid hydrate hydrochloride
(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid hydrochloride
(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid hydrochloride monohydrate
(2S)-2-(BUTYLSULFONYLAMINO)-3-[4-[4-(4-PIPERIDYL)BUTOXY]PHENYL]PROPANOIC ACID
(2S)-2-(butylsulfonylamino)-3-[4-[4-(4-piperidyl)butoxy]phenyl]propanoic acid hydrate hydrochloride
(2S)-2-(butylsulfonylamino)-3-[4-[4-(4-piperidyl)butoxy]phenyl]propanoic acid hydrochloride
(2S)-2-(Butylsulfonylamino)-3-[4-[4-(4-piperidyl)butoxy]phenyl]propanoic acid hydrochloride hydrate
(2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid
(2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid, N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
(S)-2-(BUTANE-1-SULFONYLAMINO)-3-[4-(4-PIPERIDIN-4-YL-BUTOXY)-PHENYL]-PROPIONIC ACID HCL HYDRATE
(S)-2-(butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid
(S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid hydrochloride
(S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid hydrochloride hydrate
140430-EP2277565A2
140430-EP2277566A2
140430-EP2277567A1
140430-EP2277568A2
140430-EP2277569A2
140430-EP2277570A2
140430-EP2292280A1
142373-60-2
142373-60-2 (hydrochloride)
144494-65-5
144494-65-5 (Parent)
150915-40-5
151065-53-1
373T602
494T655
6H925F8O5J
915T405
AB0005248
AB1009554
AC1L1U7L
AC1L1U7O
AC1L21WW
AC1Q3ETP
AC1Q3ETQ
AC1Q6VFB
ACT04424
AGG
Aggrastat
Aggrastat (TN)
aggrestat
Agrastat
Agrastat (TN)
AK326111
AK326170
AKOS015894972
AKOS025311245
AKOS027327567
AN-15411
AN-31474
AN-7594
API0005653
API0014445
AS-11027
AX8154227
AX8154228
BDBM50004058
BG0585
BIDD:GT0363
C07965
C22H36N2O5S
C22H36N2O5S.HCl
C22H39ClN2O6S
CAS-150915-40-5
CCG-222411
CHEBI:9605
CHEBI:9606
CHEMBL1704
CHEMBL3189072
CHEMBL916
COKMIXFXJJXBQG-NRFANRHFSA-N
CS-0948
CS-2829
CT0258
CTK4C6811
D01029
D08607
D0BN9X
DB00775
DR002726
DSSTox_CID_28561
DSSTox_GSID_48635
DSSTox_RID_82833
DTXSID20162730
DTXSID5048635
EBD44261
FT-0675251
FT-0773940
GGX234SI5H
GTPL6586
HSDB 7323
HY-17369
HY-17369B
IKE1P4X57J
J-524973
KB-269052
KB-61743
KS-00000H6G
KS-00000XQQ
L 700462
L-700,462
L-700462
L-Tyrosine, N-(butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-
L-Tyrosine, N-(butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-, monohydrochloride
L-Tyrosine, N-(butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-, monohydrochloride, monohydrate
L700462;MK383
LS-173142
LS-173214
MFCD00868210
MFCD05237246
MFCD07368623
MK 383
MK-383
MK-383 Hydrochloride
MolPort-006-167-632
MolPort-006-823-927
MolPort-027-806-963
N-(Butylsulfonyl)-4-(4-(4-piperidyl)butoxy)-L-phenylalanine monohydrochloride monohydrate
N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine monohydrochloride
N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine monohydrochloride monohydrate
N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine
N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyrosine
N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyrosine hydrochloride monohydrate
N-(BUTYLSULFONYL)-O-[4-(4-PIPERIDINYL)BUTYL]-L-TYROSINE
N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine hydrochloride
N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine Monohydrochloride Monohydrate
N-(Butylsulfonyl)-O-[4-(4-piperidynyl)butyl]-L-tyrosine Hydrochloride Hydrate
n-(butylsulfonyl)-o-[4-(piperidin-4-yl)butyl]-l-tyrosine
n-(butylsulfonyl)-o-[4-(piperidin-4-yl)butyl]-l-tyrosine hydrochloride(1:1)
N-(n-butanesulfonyl)-O-(4-(4-piperidinyl)-butyl)-(s)-tyrosine
NCGC00182085-01
NCGC00263584-01
Q-101314
RL01804
RT-016037
s3085
s8594
SC-27175
SC-96683
SCHEMBL3685
SCHEMBL41325
SCHEMBL41327
tirofiban
Tirofiban (hydrochloride monohydrate)
Tirofiban (INN)
Tirofiban [BAN:INN]
Tirofiban [INN:BAN]
Tirofiban HCl
Tirofiban HCl hydrate
Tirofiban Hydrochloride (anhydrous)
tirofiban hydrochloride (monohydrate)
Tirofiban hydrochloride (USAN)
Tirofiban hydrochloride [USAN]
Tirofiban hydrochloride anhydrous
Tirofiban hydrochloride hydrate
Tirofiban hydrochloride monohydrate
Tirofiban hydrochloride monohydrate, >=98% (HPLC)
Tirofiban, >=98.5% (HPLC)
Tirofiban, Hydrochloride Hydrate
Tirofiban[BAN:INN]
TIROFIBANHYDROCHLORIDEMONOHYDRATE
tirofibanum
Tox21_112980
Tox21_112980_1
UNII-6H925F8O5J
UNII-GGX234SI5H
UNII-IKE1P4X57J
W-5345
Y0428
ZINC3806104

US Patents and Regulatory Information for tirofiban hydrochloride

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020912-001 May 14, 1998 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020913-002 May 17, 2002 RX Yes No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020913-003 Apr 20, 2000 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020913-001 May 14, 1998 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020913-002 May 17, 2002 RX Yes No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride SOLUTION;INJECTION 020912-002 Aug 31, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020913-001 May 14, 1998 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for tirofiban hydrochloride

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Medicure AGGRASTAT tirofiban hydrochloride SOLUTION;INJECTION 020912-002 Aug 31, 2016 ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020913-002 May 17, 2002 ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020913-003 Apr 20, 2000 ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020912-001 May 14, 1998 ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020912-001 May 14, 1998 ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride SOLUTION;INJECTION 020912-002 Aug 31, 2016 ➤ Sign Up ➤ Sign Up
Medicure AGGRASTAT tirofiban hydrochloride INJECTABLE;INJECTION 020912-001 May 14, 1998 ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Supplementary Protection Certificates for tirofiban hydrochloride

Supplementary Protection Certificate SPC Country SPC Expiration SPC Description
00C/002 Belgium ➤ Sign Up PRODUCT NAME: TIROFIBANUM HYDROCHLORIDUM (EQ. TIROFIBAN); NAT. REGISTRATION NO/DATE: 922 IS 191 F 12 19990906; FIRST REGISTRATION: CH 54761 19980528
90040 Netherlands ➤ Sign Up PRODUCT NAME: TIROFIBAN, DESGEWENST IN DE VORM VAN EEN FARMACEUTISCH AAN- VAARDBAAR ZOUT OF EEN HYDRAAT, IN HET BIJZONDER TIROFIBANHY- DROCHLORIDE MONOHYDRAAT; NATL REGISTRATION NO/DATE: RVG 23380-1 19990707; FIRST REGISTRATION: DE 42618.00.00-01 19980630
C/GB99/042 United Kingdom ➤ Sign Up PRODUCT NAME: TIROFIBAN, OPTIONALLY IN THE FORM OF A PHARMACEUTICALLY ACCEPTABLE SALT, PARTICULARLY THE HYDROCHLORIDE; REGISTERED: LI 54761 19980528; CH 54761 19980528; DE 42618.00.00 19980630; DE 42618.00.01 19980630; DE 42620.00.00 19980630; DE 42620.00.01 19980630; UK PL 00025/0375 19990715; UK PL 00025/0376 19990715
/1999 Austria ➤ Sign Up PRODUCT NAME: TIROFIBAN, GEGEBENENFALLS IN DER FORM EINES PHARMAZEUTISCH ANNEHMBAREN SALZES, INSBESONDERE DES HYDROCHLORIDS; NAT. REGISTRATION NO/DATE: 1-23140 UND 1-23141 19990714; FIRST REGISTRATION: LI IKS-NR 54761 19980528
Supplementary Protection Certificate SPC Country SPC Expiration SPC Description

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Serving hundreds of leading biopharmaceutical companies globally:

Medtronic
Federal Trade Commission
Healthtrust
Merck
Dow
Argus Health
Fish and Richardson
Accenture
Moodys

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.